In an opened bottle of acetylcysteine, there may be a color change to a light purple, but it will not affect use.Īcetylcysteine should only be used with nebulizers made of plastic or glass. There may be a slight unpleasant odor when you use acetylcysteine that goes away quickly. The concentrated solution of acetylcysteine should be mixed with normal saline or sterile water and used within an hour. Only mix acetylcysteine with other medications if instructed to do so by your doctor.

Do not use more or less of it or use it more often than prescribed by your doctor. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use acetylcysteine at around the same times every day.

When given by other methods, acetylcysteine should be used as directed. When using a nebulizer, it is usually used 3 to 4 times a day. Over two-thirds of 46 placebo-controlled clinical trials with orally administered NAC have indicated beneficial effects of NAC measured either as trial endpoints or as general measures of improvement in quality of life and well-being of the patients.Acetylcysteine comes as a solution (liquid) and concentrated solution to inhale by mouth using a nebulizer (machine that turns medication into a mist that can be inhaled). NAC has been used successfully to treat GSH deficiency in a wide range of infections, genetic defects and metabolic disorders, including HIV infection and COPD. NAC, best known for its ability to counter acetaminophen toxicity, is a safe, well-tolerated antidote for cysteine/GSH deficiency. Administration of N-acetylcysteine (NAC), a cysteine prodrug, replenishes intracellular GSH levels. N2 - Glutathione (GSH) deficiency is associated with numerous pathological conditions.

T1 - N-Acetylcysteine-a safe antidote for cysteine/glutathione deficiency.

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